Amiodarone impairs trafficking through late endosomes inducing a Niemann-Pick C-like phenotype

Patients treated with amiodarone accumulate lysobisphosphatidic acid (LBPA), also known as bis(monoacylglycero)phosphate, in airway secretions and develop in different tissues vacuoles and inclusion bodies thought to originate from endosomes. To clarify the origin of these changes, we studied in vit...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Biochem Pharmacol
Main Authors: Piccoli, Elena, Nadai, Matteo, Caretta, Carla Mucignat, Bergonzini, Valeria, Del Vecchio, Claudia, Ha, Huy Riem, Bigler, Laurent, Dal Zoppo, Daniele, Faggin, Elisabetta, Pettenazzo, Andrea, Orlando, Rocco, Salata, Cristiano, Calistri, Arianna, Palù, Giorgio, Baritussio, Aldo
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier Inc. 2011
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7092840/
https://ncbi.nlm.nih.gov/pubmed/21878321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2011.07.090
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados