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Dynamics of lysosomal cholesterol in Niemann-Pick type C and normal human fibroblasts

The dynamics of endolysosomal cholesterol were investigated in Niemann-Pick type C (NPC) cells and in human fibroblasts treated with class 2 amphiphiles to mimic NPC cells. We showed through new approaches that the massive pools of endolysosomal cholesterol in these cells are not trapped but, rather...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Yvonne Lange, Jin Ye, Mike Rigney, Theodore L. Steck
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Elsevier 2002-02-01
Rangatū:Journal of Lipid Research
Ngā marau:
Urunga tuihono:http://www.sciencedirect.com/science/article/pii/S0022227520301619
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