Design of CD40 Agonists and their use in growing B cells for cancer immunotherapy

Por Kornbluth, Richard S., Stempniak, Mariusz, Stone, Geoffrey W.
Publicado em 2012

Multimeric forms of 4-1BBL as stimulators of T cells for adoptive immunotherapy

Por Kornbluth, Richard S, Snarsky, Victoria, Stone, Geoffrey W
Publicado no J Immunother Cancer (2014)

Design of vaccine adjuvants incorporating TNF superfamily ligands and TNF superfamily molecular mimics

Por Gupta, Sachin, Termini, James M., Kanagavelu, Saravana, Stone, Geoffrey W.
Publicado em 2013

Constitutively Active MAVS Inhibits HIV-1 Replication via Type I Interferon Secretion and Induction of HIV-1 Restriction Factors

Por Gupta, Sachin, Termini, James M., Issac, Biju, Guirado, Elizabeth, Stone, Geoffrey W.
Publicado no PLoS One (2016)

Vaccination with a Fusion Protein That Introduces HIV-1 Gag Antigen into a Multitrimer CD40L Construct Results in Enhanced CD8(+) T Cell Responses and Protection from Viral Challen...

Por Gupta, Sachin, Termini, James M., Raffa, Francesca N., Williams, Cindi-Ann, Kornbluth, Richard S., Stone, Geoffrey W.
Publicado em 2014

Enhancement of the priming efficacy of DNA vaccines encoding dendritic cell-targeted antigens by synergistic toll-like receptor ligands

Por Kornbluth Richard S, Stone Geoffrey W, Nabi Ghulam, Temchura Vladimir, Nchinda Godwin, Tenbusch Matthias, Grossmann Claudius, Überla Klaus
Publicado em 2009-08-01

Multimeric Soluble CD40 Ligand and GITR Ligand as Adjuvants for Human Immunodeficiency Virus DNA Vaccines

Por Stone, Geoffrey W., Barzee, Suzanne, Snarsky, Victoria, Kee, Kristin, Spina, Celsa A., Yu, Xiao-Fang, Kornbluth, Richard S.
Publicado em 2006

Enhancement of the priming efficacy of DNA vaccines encoding dendritic cell-targeted antigens by synergistic toll-like receptor ligands

Por Grossmann, Claudius, Tenbusch, Matthias, Nchinda, Godwin, Temchura, Vladimir, Nabi, Ghulam, Stone, Geoffrey W, Kornbluth, Richard S, Überla, Klaus
Publicado em 2009

EBV LMP1, a viral mimic of CD40, activates dendritic cells and functions as a molecular adjuvant when incorporated into an HIV vaccine

Por Gupta, Sachin, Termini, James M., Niu, Liguo, Kanagavelu, Saravana K., Schmidtmayerova, Helena, Snarsky, Victoria, Kornbluth, Richard S., Stone, Geoffrey W.
Publicado em 2011

A multi-trimeric fusion of CD40L and gp100 tumor antigen activates dendritic cells and enhances survival in a B16-F10 melanoma DNA vaccine model

Por Gupta, Sachin, Termini, James M, Rivas, Yaelis, Otero, Miguel, Raffa, Francesca N, Bhat, Vikas, Farooq, Amjad, Stone, Geoffrey W
Publicado no Vaccine (2015)

Peripheral T Follicular Helper Cells Are the Major HIV Reservoir within Central Memory CD4 T Cells in Peripheral Blood from Chronically HIV-Infected Individuals on Combination Anti...

Por Pallikkuth, Suresh, Sharkey, Mark, Babic, Dunja Z., Gupta, Sachin, Stone, Geoffrey W., Fischl, Margaret A., Stevenson, Mario, Pahwa, Savita
Publicado no J Virol (2016)

Nanoparticle-Delivered Multimeric Soluble CD40L DNA Combined with Toll-Like Receptor Agonists as a Treatment for Melanoma

Por Stone, Geoffrey W., Barzee, Suzanne, Snarsky, Victoria, Santucci, Camila, Tran, Brian, Langer, Robert, Zugates, Gregory T., Anderson, Daniel G., Kornbluth, Richard S.
Publicado em 2009

CD40L expressed from the canarypox vector, ALVAC, can boost immunogenicity of HIV-1 canarypox vaccine in mice and enhance the in-vitro expansion of viral specific CD8(+) T cell mem...

Por Liu, Jun, Yu, Qigui, Stone, Geoffrey W., Yue, Feng Yun, Ngai, Nicholas, Jones, R. Brad, Kornbluth, Richard S., Ostrowski, Mario A.
Publicado em 2008

Latent Membrane Protein 1 as a molecular adjuvant for single-cycle lentiviral vaccines

Por Gupta, Sachin, Termini, James M, Niu, Liguo, Kanagavelu, Saravana K, Rahmberg, Andrew R, Kornbluth, Richard S, Evans, David T, Stone, Geoffrey W
Publicado em 2011

HIV-1 Adenoviral Vector Vaccines Expressing Multi-Trimeric BAFF and 4-1BBL Enhance T Cell Mediated Anti-Viral Immunity

Por Kanagavelu, Saravana, Termini, James M., Gupta, Sachin, Raffa, Francesca N., Fuller, Katherine A., Rivas, Yaelis, Philip, Sakhi, Kornbluth, Richard S., Stone, Geoffrey W.
Publicado em 2014

Soluble multi-trimeric TNF superfamily ligand adjuvants enhance immune responses to a HIV-1 Gag DNA vaccine

Por Kanagavelu, Saravana K., Snarsky, Victoria, Termini, James M., Gupta, Sachin, Barzee, Suzanne, Wright, Jacqueline A., Khan, Wasif N., Kornbluth, Richard S., Stone, Geoffrey W.
Publicado em 2011

Macaque Multimeric Soluble CD40 Ligand and GITR Ligand Constructs Are Immunostimulatory Molecules In Vitro

Por Stone, Geoffrey W., Barzee, Suzanne, Snarsky, Victoria, Spina, Celsa A., Lifson, Jeffrey D., Pillai, Vinod Kumar Bhaskara, Amara, Rama Rao, Villinger, François, Kornbluth, Richard S.
Publicado em 2006

Mechanism of Action of NB2001 and NB2030, Novel Antibacterial Agents Activated by β-Lactamases

Por Stone, Geoffrey W., Zhang, Qin, Castillo, Rosario, Doppalapudi, V. Ramana, Bueno, Analia R., Lee, Jean Y., Li, Qing, Sergeeva, Maria, Khambatta, Gody, Georgopapadakou, Nafsika H.
Publicado em 2004

DNA Vaccine Molecular Adjuvants SP-D-BAFF and SP-D-APRIL Enhance Anti-gp120 Immune Response and Increase HIV-1 Neutralizing Antibody Titers

Por Gupta, Sachin, Clark, Emily S., Termini, James M., Boucher, Justin, Kanagavelu, Saravana, LeBranche, Celia C., Abraham, Sakhi, Montefiori, David C., Khan, Wasif N., Stone, Geoffrey W.
Publicado no J Virol (2015)

Preclinical evaluation of HIV-1 therapeutic ex vivo dendritic cell vaccines expressing consensus Gag antigens and conserved Gag epitopes

Por Niu, Liguo, Termini, James M., Kanagavelu, Saravana K., Gupta, Sachin, Rolland, Morgane M., Kulkarni, Viraj, Pavlakis, George N., Felber, Barbara K., Mullins, James I., Fischl, Margaret A., Stone, Geoffrey W.
Publicado em 2011