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Mechanism of Action of NB2001 and NB2030, Novel Antibacterial Agents Activated by β-Lactamases
Two potent antibacterial agents designed to undergo enzyme-catalyzed therapeutic activation were evaluated for their mechanisms of action. The compounds, NB2001 and NB2030, contain a cephalosporin with a thienyl (NB2001) or a tetrazole (NB2030) ring at the C-7 position and are linked to the antibact...
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| Hauptverfasser: | , , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Microbiology
2004
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC321519/ https://ncbi.nlm.nih.gov/pubmed/14742198 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.2.477-483.2004 |
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