Latent Membrane Protein 1 as a molecular adjuvant for single-cycle lentiviral vaccines

BACKGROUND: Molecular adjuvants are a promising method to enhance virus-specific immune responses and protect against HIV-1 infection. Immune activation by ligands for receptors such as CD40 can induce dendritic cell activation and maturation. Here we explore the incorporation of two CD40 mimics, Ep...

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Main Authors: Gupta, Sachin, Termini, James M, Niu, Liguo, Kanagavelu, Saravana K, Rahmberg, Andrew R, Kornbluth, Richard S, Evans, David T, Stone, Geoffrey W
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2011
Assuntos:
Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3118346/
https://ncbi.nlm.nih.gov/pubmed/21592361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-8-39
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