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Epstein Barr virus Latent Membrane Protein-1 enhances dendritic cell therapy lymph node migration, activation, and IL-12 secretion

Dendritic cells (DC) are a promising cell type for cancer vaccines due to their high immunostimulatory capacity. However, improper maturation of DC prior to treatment may account for the limited efficacy of DC vaccine clinical trials. Latent Membrane Protein-1 (LMP1) of Epstein-Barr virus was examin...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Termini, James M., Gupta, Sachin, Raffa, Francesca N., Guirado, Elizabeth, Fischl, Margaret A., Niu, Liguo, Kanagavelu, Saravana, Stone, Geoffrey W.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5599068/
https://ncbi.nlm.nih.gov/pubmed/28910387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0184915
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