Epstein Barr virus Latent Membrane Protein-1 enhances dendritic cell therapy lymph node migration, activation, and IL-12 secretion

Dendritic cells (DC) are a promising cell type for cancer vaccines due to their high immunostimulatory capacity. However, improper maturation of DC prior to treatment may account for the limited efficacy of DC vaccine clinical trials. Latent Membrane Protein-1 (LMP1) of Epstein-Barr virus was examin...

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Publicado en:PLoS One
Main Authors: Termini, James M., Gupta, Sachin, Raffa, Francesca N., Guirado, Elizabeth, Fischl, Margaret A., Niu, Liguo, Kanagavelu, Saravana, Stone, Geoffrey W.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2017
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5599068/
https://ncbi.nlm.nih.gov/pubmed/28910387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0184915
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