Preclinical evaluation of HIV-1 therapeutic ex vivo dendritic cell vaccines expressing consensus Gag antigens and conserved Gag epitopes

BACKGROUND: Dendritic cell (DC) therapy is a promising technology for the treatment of HIV infected individuals. HIV-1 Gag- and Nef RNA-loaded DC have previously been shown to induce immune responses ex vivo following coculture with autologous lymphocytes. However, polyfunctionality and memory respo...

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Hauptverfasser: Niu, Liguo, Termini, James M., Kanagavelu, Saravana K., Gupta, Sachin, Rolland, Morgane M., Kulkarni, Viraj, Pavlakis, George N., Felber, Barbara K., Mullins, James I., Fischl, Margaret A., Stone, Geoffrey W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3046258/
https://ncbi.nlm.nih.gov/pubmed/21241732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2010.12.131
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