A Direct Method to Determine the Strength of the Dermal – Epidermal Junction in a Mouse Model for Epidermolysis Bullosa

Por Sproule, Thomas J., Roopenian, Derry C., Sundberg, John P.
Publicado em 2012

The MHC class I–like Fc receptor promotes humorally mediated autoimmune disease

Por Akilesh, Shreeram, Petkova, Stefka, Sproule, Thomas J., Shaffer, Daniel J., Christianson, Gregory J., Roopenian, Derry
Publicado em 2004

CD8(+) T regulatory cells express the Ly49 Class I MHC receptor and are defective in autoimmune prone B6-Yaa mice

Por Kim, Hye-Jung, Wang, Xuan, Radfar, Soroosh, Sproule, Thomas J., Roopenian, Derry C., Cantor, Harvey
Publicado em 2011

Minor genomic differences between related B6 and B10 mice affect severity of schistosome infection by governing the mode of dendritic cell activation

Por Smith, Patrick M., Sproule, Thomas J., Philip, Vivek M., Roopenian, Derry C., Stadecker, Miguel J.
Publicado no Eur J Immunol (2015)

A Single-Amino-Acid Variant of the H60 CD8 Epitope Generates Specific Immunity with Diverse TCR Recruitment

Por Ryu, Su Jeong, Jeon, Ji Yeong, Chang, Jun, Sproule, Thomas J., Roopenian, Derry C., Choi, Eun Young
Publicado em 2012

Albumin-deficient mouse models for studying metabolism of human albumin and pharmacokinetics of albumin-based drugs

Por Roopenian, Derry C, Low, Benjamin E, Christianson, Gregory J, Proetzel, Gabriele, Sproule, Thomas J, Wiles, Michael V
Publicado no MAbs (2015)

Human antibodies induce arthritis in mice deficient in the low-affinity inhibitory IgG receptor FcγRIIB

Por Petkova, Stefka B., Konstantinov, Konstantin N., Sproule, Thomas J., Lyons, Bonnie L., Awwami, Moheeb Al, Roopenian, Derry C.
Publicado em 2006

Naturally variant autosomal and sex-linked loci determine the severity of iron overload in β(2)-microglobulin-deficient mice

Por Sproule, Thomas J., Jazwinska, Elizabeth C., Britton, Robert S., Bacon, Bruce R., Fleming, Robert E., Sly, William S., Roopenian, Derry C.
Publicado em 2001

A Mouse Model of Generalized non-Herlitz Junctional Epidermolysis Bullosa

Por Bubier, Jason A., Sproule, Thomas J., Petell, Lydia, Webb, Cameron, Fine, Jo-David, Roopenian, Derry C., Sundberg, John P.
Publicado em 2010

A Mouse Model of Heritable Cerebrovascular Disease

Por Sproule, Thomas J., Sled, John G., Wentzell, Jill, Wang, Bing, Henkelman, R. Mark, Roopenian, Derry C., Burgess, Robert W.
Publicado em 2010

Interleukin 6 Accelerates Mortality by Promoting the Progression of the Systemic Lupus Erythematosus-Like Disease of BXSB.Yaa Mice

Por Jain, Shweta, Park, Giljun, Sproule, Thomas J., Christianson, Gregory J., Leeth, Caroline M., Wang, Hongsheng, Roopenian, Derry C., Morse, Herbert C.
Publicado no PLoS One (2016)

A critical role for IL-21 receptor signaling in the pathogenesis of systemic lupus erythematosus in BXSB-Yaa mice

Por Bubier, Jason A., Sproule, Thomas J., Foreman, Oded, Spolski, Rosanne, Shaffer, Daniel J., Morse, Herbert C., Leonard, Warren J., Roopenian, Derry C.
Publicado em 2009

Coronary Artery Disease From Isolated Non-H2-Determined Incompatibilities in Transplanted Mouse Hearts

Por Russell, Paul S., Chase, Catharine M., Madsen, Joren C., Hirohashi, Tsutomu, Cornell, Lynn D., Sproule, Thomas J., Colvin, Robert B., Roopenian, Derry C.
Publicado em 2011

Enhanced antibody half-life improves in vivo activity

Por Zalevsky, Jonathan, Chamberlain, Aaron K., Horton, Holly M., Karki, Sher, Leung, Irene W.L., Sproule, Thomas J., Lazar, Greg A., Roopenian, Derry C., Desjarlais, John R.
Publicado em 2010

Diverse dystonin gene mutations cause distinct patterns of Dst isoform deficiency and phenotypic heterogeneity in Dystonia musculorum mice

Por Yoshioka, Nozomu, Kabata, Yudai, Kuriyama, Momona, Bizen, Norihisa, Zhou, Li, Tran, Dang M., Yano, Masato, Yoshiki, Atsushi, Ushiki, Tatsuo, Sproule, Thomas J., Abe, Riichiro, Takebayashi, Hirohide
Publicado no Dis Model Mech (2020)

MHC Class I Family Proteins Retard SLE Autoimmunity and B Cell Lymphomagenesis

Por McPhee, Caroline G., Sproule, Thomas J., Shin, Dong-Mi, Bubier, Jason A., Schott, William H., Steinbuck, Martin P., Avenesyan, Lia, Morse, Herbert C., Roopenian, Derry. C.
Publicado em 2011

Interleukin 21 Is a Double-Edged Sword in the SLE-like Disease of BXSB.Yaa Mice

Por McPhee, Caroline G., Bubier, Jason A., Sproule, Thomas J., Park, Giljun, Steinbuck, Martin P., Schott, William H., Christianson, Gregory J., Morse, Herbert C., Roopenian, Derry C.
Publicado em 2013

Molecular Identification of Collagen 17a1 as a Major Genetic Modifier of Laminin Gamma 2 Mutation-Induced Junctional Epidermolysis Bullosa in Mice

Por Sproule, Thomas J., Bubier, Jason A., Grandi, Fiorella C., Sun, Victor Z., Philip, Vivek M., McPhee, Caroline G., Adkins, Elisabeth B., Sundberg, John P., Roopenian, Derry C.
Publicado em 2014

Structural Variant in Mitochondrial-Associated Gene (MRPL3) Induces Adult-Onset Neurodegeneration with Memory Impairment in the Mouse

Por Cahill, Lindsay S., Cameron, Jessie M., Winterburn, Julie, Macos, Patrick, Hoggarth, Johnathan, Dzamba, Misko, Brudno, Michael, Nutter, Lauryl M. J., Sproule, Thomas J., Burgess, Robert W., Henkelman, R. Mark, Sled, John G.
Publicado no J Neurosci (2020)

Precocious Interleukin 21 Expression in Naïve Mice Identifies a Natural Helper Cell Population in Autoimmune Disease

Por Marnik, Elisabeth A., Wang, Xulong, Sproule, Thomas J., Park, Giljun, Christianson, Gregory J., Lane-Reticker, Sarah Kate, Jain, Shweta, Duffy, Theodore, Wang, Hongsheng, Carter, Gregory W., Morse, Herbert C., Roopenian, Derry C.
Publicado no Cell Rep (2017)