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Naturally variant autosomal and sex-linked loci determine the severity of iron overload in β(2)-microglobulin-deficient mice
Hereditary hemochromatosis (HH) is a common chronic human genetic disorder whose hallmark is systemic iron overload. Homozygosity for a mutation in the MHC class I heavy chain paralogue gene HFE has been found to be a primary cause of HH. However, many individuals homozygous for the defective allele...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The National Academy of Sciences
2001
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC33182/ https://ncbi.nlm.nih.gov/pubmed/11309500 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.091088998 |
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