Global Transcriptional Response to Hfe Deficiency and Dietary Iron Overload in Mouse Liver and Duodenum

Iron is an essential trace element whose absorption is usually tightly regulated in the duodenum. HFE-related hereditary hemochromatosis (HH) is characterized by abnormally low expression of the iron-regulatory hormone, hepcidin, which results in increased iron absorption. The liver is crucial for i...

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Main Authors: Rodriguez, Alejandra, Luukkaala, Tiina, Fleming, Robert E., Britton, Robert S., Bacon, Bruce R., Parkkila, Seppo
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2009
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2747280/
https://ncbi.nlm.nih.gov/pubmed/19787063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0007212
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