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Global Transcriptional Response to Hfe Deficiency and Dietary Iron Overload in Mouse Liver and Duodenum

Iron is an essential trace element whose absorption is usually tightly regulated in the duodenum. HFE-related hereditary hemochromatosis (HH) is characterized by abnormally low expression of the iron-regulatory hormone, hepcidin, which results in increased iron absorption. The liver is crucial for i...

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Détails bibliographiques
Auteurs principaux: Rodriguez, Alejandra, Luukkaala, Tiina, Fleming, Robert E., Britton, Robert S., Bacon, Bruce R., Parkkila, Seppo
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2747280/
https://ncbi.nlm.nih.gov/pubmed/19787063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0007212
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