Association of HFE protein with transferrin receptor in crypt enterocytes of human duodenum

In hereditary hemochromatosis (HH), intestinal absorption of dietary iron is increased, leading to excessive iron accumulation in tissues and resultant organ damage. The HFE protein, which is defective in HH, normally is expressed in crypt enterocytes of the duodenum where it has a unique, predomina...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Waheed, Abdul, Parkkila, Seppo, Saarnio, Juha, Fleming, Robert E., Zhou, Xiao Yan, Tomatsu, Shunji, Britton, Robert S., Bacon, Bruce R., Sly, William S.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1999
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC15523/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9990067/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.4.1579
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