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HFE gene knockout produces mouse model of hereditary hemochromatosis

Hereditary hemochromatosis (HH) is a common autosomal recessive disease characterized by increased iron absorption and progressive iron storage that results in damage to major organs in the body. Recently, a candidate gene for HH called HFE encoding a major histocompatibility complex class I-like pr...

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Publicado no:Proc Natl Acad Sci U S A
Principais autores: Zhou, Xiao Yan, Tomatsu, Shunji, Fleming, Robert E., Parkkila, Seppo, Waheed, Abdul, Jiang, Jinxing, Fei, Ying, Brunt, Elizabeth M., Ruddy, David A., Prass, Cynthia E., Schatzman, Randall C., O’Neill, Rosemary, Britton, Robert S., Bacon, Bruce R., Sly, William S.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1998
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC19387/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9482913/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.5.2492
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