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Mouse strain differences determine severity of iron accumulation in Hfe knockout model of hereditary hemochromatosis
Hereditary hemochromatosis (HH) is a common disorder of iron metabolism caused by mutation in HFE, a gene encoding an MHC class I-like protein. Clinical studies demonstrate that the severity of iron loading is highly variable among individuals with identical HFE genotypes. To determine whether genet...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The National Academy of Sciences
2001
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC30203/ https://ncbi.nlm.nih.gov/pubmed/11226304 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.051630898 |
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