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Association of HFE protein with transferrin receptor in crypt enterocytes of human duodenum

In hereditary hemochromatosis (HH), intestinal absorption of dietary iron is increased, leading to excessive iron accumulation in tissues and resultant organ damage. The HFE protein, which is defective in HH, normally is expressed in crypt enterocytes of the duodenum where it has a unique, predomina...

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Autors principals: Waheed, Abdul, Parkkila, Seppo, Saarnio, Juha, Fleming, Robert E., Zhou, Xiao Yan, Tomatsu, Shunji, Britton, Robert S., Bacon, Bruce R., Sly, William S.
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences 1999
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC15523/
https://ncbi.nlm.nih.gov/pubmed/9990067
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