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Regulation of transferrin-mediated iron uptake by HFE, the protein defective in hereditary hemochromatosis

The protein defective in hereditary hemochromatosis, called HFE, is similar to MHC class I-type proteins and associates with β(2)-microglobulin (β(2)M). Its association with β(2)M was previously shown to be necessary for its stability, normal intracellular processing, and cell surface expression in...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Waheed, Abdul, Grubb, Jeffrey H., Zhou, Xiao Yan, Tomatsu, Shunji, Fleming, Robert E., Costaldi, Mark E., Britton, Robert S., Bacon, Bruce R., Sly, William S.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2002
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC122482/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11867720/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.042701499
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