Regulation of transferrin-mediated iron uptake by HFE, the protein defective in hereditary hemochromatosis

The protein defective in hereditary hemochromatosis, called HFE, is similar to MHC class I-type proteins and associates with β(2)-microglobulin (β(2)M). Its association with β(2)M was previously shown to be necessary for its stability, normal intracellular processing, and cell surface expression in...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Waheed, Abdul, Grubb, Jeffrey H., Zhou, Xiao Yan, Tomatsu, Shunji, Fleming, Robert E., Costaldi, Mark E., Britton, Robert S., Bacon, Bruce R., Sly, William S.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 2002
Soggetti:	Biological Sciences
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC122482/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11867720/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.042701499
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