Regulation of transferrin-mediated iron uptake by HFE, the protein defective in hereditary hemochromatosis

The protein defective in hereditary hemochromatosis, called HFE, is similar to MHC class I-type proteins and associates with β(2)-microglobulin (β(2)M). Its association with β(2)M was previously shown to be necessary for its stability, normal intracellular processing, and cell surface expression in...

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Main Authors: Waheed, Abdul, Grubb, Jeffrey H., Zhou, Xiao Yan, Tomatsu, Shunji, Fleming, Robert E., Costaldi, Mark E., Britton, Robert S., Bacon, Bruce R., Sly, William S.
Format: Artigo
Jezik:Inglês
Izdano: The National Academy of Sciences 2002
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC122482/
https://ncbi.nlm.nih.gov/pubmed/11867720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.042701499
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