The MHC class I–like Fc receptor promotes humorally mediated autoimmune disease

The MHC class I family–like Fc receptor, FcRn, is normally responsible for extending the life span of serum IgG Ab’s, but whether this molecule contributes to autoimmune pathogenesis remains speculative. To determine directly whether this function contributes to humoral autoimmune disease, we examin...

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Hlavní autoři: Akilesh, Shreeram, Petkova, Stefka, Sproule, Thomas J., Shaffer, Daniel J., Christianson, Gregory J., Roopenian, Derry
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2004
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC398424/
https://ncbi.nlm.nih.gov/pubmed/15124024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200418838
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