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The MHC class I–like Fc receptor promotes humorally mediated autoimmune disease

The MHC class I family–like Fc receptor, FcRn, is normally responsible for extending the life span of serum IgG Ab’s, but whether this molecule contributes to autoimmune pathogenesis remains speculative. To determine directly whether this function contributes to humoral autoimmune disease, we examin...

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Detalhes bibliográficos
Main Authors: Akilesh, Shreeram, Petkova, Stefka, Sproule, Thomas J., Shaffer, Daniel J., Christianson, Gregory J., Roopenian, Derry
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC398424/
https://ncbi.nlm.nih.gov/pubmed/15124024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200418838
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