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Monoclonal antibodies directed against human FcRn and their applications
The MHC class I-like Fc receptor (FcRn) is an intracellular trafficking Fc receptor that is uniquely responsible for the extended serum half-life of antibodies of the IgG subclass and their ability to transport across cellular barriers. By performing these functions, FcRn affects numerous facets of...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Landes Bioscience
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3361656/ https://ncbi.nlm.nih.gov/pubmed/22453095 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/mabs.4.2.19397 |
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