Monoclonal antibodies directed against human FcRn and their applications

The MHC class I-like Fc receptor (FcRn) is an intracellular trafficking Fc receptor that is uniquely responsible for the extended serum half-life of antibodies of the IgG subclass and their ability to transport across cellular barriers. By performing these functions, FcRn affects numerous facets of...

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Hlavní autoři: Christianson, Gregory J, Sun, Victor Z, Akilesh, Shreeram, Pesavento, Emanuele, Proetzel, Gabriele, Roopenian, Derry C
Médium: Artigo
Jazyk:Inglês
Vydáno: Landes Bioscience 2012
Témata:
Report
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3361656/
https://ncbi.nlm.nih.gov/pubmed/22453095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/mabs.4.2.19397
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