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Monoclonal antibodies directed against human FcRn and their applications

The MHC class I-like Fc receptor (FcRn) is an intracellular trafficking Fc receptor that is uniquely responsible for the extended serum half-life of antibodies of the IgG subclass and their ability to transport across cellular barriers. By performing these functions, FcRn affects numerous facets of...

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Bibliografische gegevens
Hoofdauteurs: Christianson, Gregory J, Sun, Victor Z, Akilesh, Shreeram, Pesavento, Emanuele, Proetzel, Gabriele, Roopenian, Derry C
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Landes Bioscience 2012
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3361656/
https://ncbi.nlm.nih.gov/pubmed/22453095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/mabs.4.2.19397
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