Analytical FcRn affinity chromatography for functional characterization of monoclonal antibodies

The neonatal Fc receptor (FcRn) is important for the metabolic fate of IgG antibodies in vivo. Analysis of the interaction between FcRn and IgG in vitro might provide insight into the structural and functional integrity of therapeutic IgG that may affect pharmacokinetics (PK) in vivo. We developed a...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Schlothauer, Tilman, Rueger, Petra, Stracke, Jan Olaf, Hertenberger, Hubert, Fingas, Felix, Kling, Lothar, Emrich, Thomas, Drabner, Georg, Seeber, Stefan, Auer, Johannes, Koch, Stefan, Papadimitriou, Apollon
Formato: Artigo
Idioma:Inglês
Publicado: Landes Bioscience 2013
Assuntos:
Report
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3906311/
https://ncbi.nlm.nih.gov/pubmed/23765230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/mabs.24981
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares