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Humanized FcRn Mouse Models for Evaluating Pharmacokinetics of human IgG Antibodies
A key element for the successful development of novel therapeutic antibodies is to fully understand their pharmacokinetic and pharmacodynamic behavior before performing clinical trials. While many in vitro modeling approaches exist, these simply cannot substitute for data obtained from appropriate a...
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| Главные авторы: | , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2013
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3858440/ https://ncbi.nlm.nih.gov/pubmed/23867339 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymeth.2013.07.005 |
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