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FcRn receptor-mediated pharmacokinetics of therapeutic IgG in the eye

PURPOSE: The goal of this study was to determine the role of the neonatal Fc (FcRn) receptor in eliminating intravitreally administered full-length immunoglobulin G (IgG) across the blood-retinal barrier. METHODS: FcRn receptor expression in normal and laser photocoagulated retinas was compared quan...

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Autors principals: Kim, Hyuncheol, Robinson, Shaun B., Csaky, Karl G.
Format: Artigo
Idioma:Inglês
Publicat: Molecular Vision 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2794657/
https://ncbi.nlm.nih.gov/pubmed/20019892
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