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Efficient Mucosal Delivery of Vaccine Using the FcRn-Mediated IgG Transfer Pathway

Vaccine strategies to prevent invasive mucosal pathogens are being sought because 80–90% of infectious diseases are initiated at mucosal surfaces. However, our ability to deliver an intact vaccine antigen across a mucosal barrier for induction of effective immunity is limited. The neonatal Fc recept...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Ye, Lilin, Zeng, Rongyu, Bai, Yu, Roopenian, Derry C., Zhu, Xiaoping
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3197702/
https://ncbi.nlm.nih.gov/pubmed/21240266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt.1742
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