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Podocytes use FcRn to clear IgG from the glomerular basement membrane
The glomerular filtration barrier prevents large serum proteins from being lost into the urine. It is not known, however, why the filter does not routinely clog with large proteins that enter the glomerular basement membrane (GBM). Here, we provide evidence that an active transport mechanism exists...
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| Hauptverfasser: | , , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2008
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2242706/ https://ncbi.nlm.nih.gov/pubmed/18198272 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0711515105 |
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