Podocytes use FcRn to clear IgG from the glomerular basement membrane

The glomerular filtration barrier prevents large serum proteins from being lost into the urine. It is not known, however, why the filter does not routinely clog with large proteins that enter the glomerular basement membrane (GBM). Here, we provide evidence that an active transport mechanism exists...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Akilesh, Shreeram, Huber, Tobias B., Wu, Hui, Wang, Gary, Hartleben, Björn, Kopp, Jeffrey B., Miner, Jeffrey H., Roopenian, Derry C., Unanue, Emil R., Shaw, Andrey S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2008
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2242706/
https://ncbi.nlm.nih.gov/pubmed/18198272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0711515105
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi