Podocytes use FcRn to clear IgG from the glomerular basement membrane

The glomerular filtration barrier prevents large serum proteins from being lost into the urine. It is not known, however, why the filter does not routinely clog with large proteins that enter the glomerular basement membrane (GBM). Here, we provide evidence that an active transport mechanism exists...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Akilesh, Shreeram, Huber, Tobias B., Wu, Hui, Wang, Gary, Hartleben, Björn, Kopp, Jeffrey B., Miner, Jeffrey H., Roopenian, Derry C., Unanue, Emil R., Shaw, Andrey S.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: National Academy of Sciences 2008
विषय:
Biological Sciences
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC2242706/
https://ncbi.nlm.nih.gov/pubmed/18198272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0711515105
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