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Transfer of IgG in the female genital tract by MHC class I-related neonatal Fc receptor (FcRn) confers protective immunity to vaginal infection

IgG is a major Ig subclass in mucosal secretions of the human female genital tract, where it predominates over the IgA isotype. Despite the abundance of IgG, surprisingly little is known about where and how IgG enters the lumen of the genital tract and the exact role local IgG plays in preventing se...

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Bibliographische Detailangaben
Hauptverfasser: Li, Zili, Palaniyandi, Senthilkumar, Zeng, Rongyu, Tuo, Wenbin, Roopenian, Derry C., Zhu, Xiaoping
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3060240/
https://ncbi.nlm.nih.gov/pubmed/21368166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1012861108
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