Transfer of IgG in the female genital tract by MHC class I-related neonatal Fc receptor (FcRn) confers protective immunity to vaginal infection

IgG is a major Ig subclass in mucosal secretions of the human female genital tract, where it predominates over the IgA isotype. Despite the abundance of IgG, surprisingly little is known about where and how IgG enters the lumen of the genital tract and the exact role local IgG plays in preventing se...

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Detaylı Bibliyografya
Asıl Yazarlar: Li, Zili, Palaniyandi, Senthilkumar, Zeng, Rongyu, Tuo, Wenbin, Roopenian, Derry C., Zhu, Xiaoping
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2011
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3060240/
https://ncbi.nlm.nih.gov/pubmed/21368166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1012861108
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