Malaria vaccines: identifying Plasmodium falciparum liver-stage targets

Por Longley, Rhea J., Hill, Adrian V. S., Spencer, Alexandra J.
Publicado no Front Microbiol (2015)

Protection from liver-stage malaria is dependent on a fine balance between the number of infected hepatocytes and effector CD8(+) T cells

Por Spencer, Alexandra, Longley, Rhea, Gola, Anita, Lambe, Teresa, Hill, Adrian
Publicado em 2014

Deletion of Fifteen Open Reading Frames from Modified Vaccinia Virus Ankara Fails to Improve Immunogenicity

Por Alharbi, Naif Khalaf, Spencer, Alexandra J., Hill, Adrian V. S., Gilbert, Sarah C.
Publicado no PLoS One (2015)

Development of an In Vitro Assay and Demonstration of Plasmodium berghei Liver-Stage Inhibition by TRAP-Specific CD8(+) T Cells

Por Longley, Rhea J., Bauza, Karolis, Ewer, Katie J., Hill, Adrian V. S., Spencer, Alexandra J.
Publicado no PLoS One (2015)

Identification of Immunodominant Responses to the Plasmodium falciparum Antigens PfUIS3, PfLSA1 and PfLSAP2 in Multiple Strains of Mice

Por Longley, Rhea J., Halbroth, Benedict R., Ewer, Katie J., Hill, Adrian V. S., Spencer, Alexandra J.
Publicado no PLoS One (2015)

The Threshold of Protection from Liver-Stage Malaria Relies on a Fine Balance between the Number of Infected Hepatocytes and Effector CD8(+) T Cells Present in the Liver

Por Spencer, Alexandra J., Longley, Rhea J., Gola, Anita, Ulaszewska, Marta, Lambe, Teresa, Hill, Adrian V. S.
Publicado no J Immunol (2017)

Recombination-Mediated Genetic Engineering of a Bacterial Artificial Chromosome Clone of Modified Vaccinia virus Ankara (MVA)

Por Cottingham, Matthew G., Andersen, Rikke F., Spencer, Alexandra J., Saurya, Saroj, Furze, Julie, Hill, Adrian V. S., Gilbert, Sarah C.
Publicado em 2008

Correction: Recombination-Mediated Genetic Engineering of a Bacterial Artificial Chromosome Clone of Modified Vaccinia virus Ankara (MVA)

Por Cottingham, Matthew G., Andersen, Rikke F., Spencer, Alexandra J., Saurya, Saroj, Furze, Julie, Hill, Adrian V. S., Gilbert, Sarah C.
Publicado em 2011

Recombinant Viral Vectored Vaccines Expressing Plasmodium chabaudi AS Apical Membrane Antigen 1: Mechanisms of Vaccine-Induced Blood-Stage Protection

Por Biswas, Sumi, Spencer, Alexandra J., Forbes, Emily K., Gilbert, Sarah C., Holder, Anthony A., Hill, Adrian V. S., Draper, Simon J.
Publicado em 2012

The relative magnitude of transgene-specific adaptive immune responses induced by human and chimpanzee adenovirus vectors differs between laboratory animals and a target species

Por Dicks, Matthew D.J., Guzman, Efrain, Spencer, Alexandra J., Gilbert, Sarah C., Charleston, Bryan, Hill, Adrian V.S., Cottingham, Matthew G.
Publicado no Vaccine (2015)

Differential immunogenicity between HAdV-5 and chimpanzee adenovirus vector ChAdOx1 is independent of fiber and penton RGD loop sequences in mice

Por Dicks, Matthew D. J., Spencer, Alexandra J., Coughlan, Lynda, Bauza, Karolis, Gilbert, Sarah C., Hill, Adrian V. S., Cottingham, Matthew G.
Publicado no Sci Rep (2015)

A Novel Chimpanzee Adenovirus Vector with Low Human Seroprevalence: Improved Systems for Vector Derivation and Comparative Immunogenicity

Por Dicks, Matthew D. J., Spencer, Alexandra J., Edwards, Nick J., Wadell, Göran, Bojang, Kalifa, Gilbert, Sarah C., Hill, Adrian V. S., Cottingham, Matthew G.
Publicado em 2012

Comparative assessment of vaccine vectors encoding ten malaria antigens identifies two protective liver-stage candidates

Por Longley, Rhea J., Salman, Ahmed M., Cottingham, Matthew G., Ewer, Katie, Janse, Chris J., Khan, Shahid M., Spencer, Alexandra J., Hill, Adrian V. S.
Publicado no Sci Rep (2015)

Immunity Against Heterosubtypic Influenza Virus Induced By Adenovirus And MVA Expressing Nucleoprotein And Matrix Protein-1

Por Lambe, Teresa, Carey, John B., Li, Yuanyuan, Spencer, Alexandra J., van Laarhoven, Arjan, Mullarkey, Caitlin E., Vrdoljak, Anto, Moore, Anne C., Gilbert, Sarah C.
Publicado em 2013

Enhanced Vaccine-Induced CD8(+) T Cell Responses to Malaria Antigen ME-TRAP by Fusion to MHC Class II Invariant Chain

Por Spencer, Alexandra J., Cottingham, Matthew G., Jenks, Jennifer A., Longley, Rhea J., Capone, Stefania, Colloca, Stefano, Folgori, Antonella, Cortese, Riccardo, Nicosia, Alfredo, Bregu, Migena, Hill, Adrian V. S.
Publicado em 2014

Assessment of the Plasmodium falciparum Preerythrocytic Antigen UIS3 as a Potential Candidate for a Malaria Vaccine

Por Longley, Rhea J., Halbroth, Benedict R., Salman, Ahmed M., Ewer, Katie J., Hodgson, Susanne H., Janse, Chris J., Khan, Shahid M., Hill, Adrian V. S., Spencer, Alexandra J.
Publicado no Infect Immun (2017)

4-1BBL Enhances CD8(+) T Cell Responses Induced by Vectored Vaccines in Mice but Fails to Improve Immunogenicity in Rhesus Macaques

Por Spencer, Alexandra J., Furze, Julie, Honeycutt, Jared D., Calvert, Alice, Saurya, Saroj, Colloca, Stefano, Wyllie, David H., Gilbert, Sarah C., Bregu, Migena, Cottingham, Matthew G., Hill, Adrian V. S.
Publicado em 2014

A T Cell-Inducing Influenza Vaccine for the Elderly: Safety and Immunogenicity of MVA-NP+M1 in Adults Aged over 50 Years

Por Antrobus, Richard D., Lillie, Patrick J., Berthoud, Tamara K., Spencer, Alexandra J., McLaren, James E., Ladell, Kristin, Lambe, Teresa, Milicic, Anita, Price, David A., Hill, Adrian V. S., Gilbert, Sarah C.
Publicado em 2012

Fusion of the Mycobacterium tuberculosis Antigen 85A to an Oligomerization Domain Enhances Its Immunogenicity in Both Mice and Non-Human Primates

Por Spencer, Alexandra J., Hill, Fergal, Honeycutt, Jared D., Cottingham, Matthew G., Bregu, Migena, Rollier, Christine S., Furze, Julie, Draper, Simon J., Søgaard, Karen C., Gilbert, Sarah C., Wyllie, David H., Hill, Adrian V. S.
Publicado em 2012

Immunogenicity and efficacy of a chimpanzee adenovirus-vectored Rift Valley Fever vaccine in mice

Por Warimwe, George M, Lorenzo, Gema, Lopez-Gil, Elena, Reyes-Sandoval, Arturo, Cottingham, Matthew G, Spencer, Alexandra J, Collins, Katharine A, Dicks, Matthew DJ, Milicic, Anita, Lall, Amar, Furze, Julie, Turner, Alison V, Hill, Adrian VS, Brun, Alejandro, Gilbert, Sarah C
Publicado no Virol J (2013)