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Enhanced Vaccine-Induced CD8(+) T Cell Responses to Malaria Antigen ME-TRAP by Fusion to MHC Class II Invariant Chain
The orthodox role of the invariant chain (CD74; Ii) is in antigen presentation to CD4(+) T cells, but enhanced CD8(+) T cells responses have been reported after vaccination with vectored viral vaccines encoding a fusion of Ii to the antigen of interest. In this study we assessed whether fusion of th...
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| Main Authors: | , , , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4063960/ https://ncbi.nlm.nih.gov/pubmed/24945248 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0100538 |
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