Fusion of HCV Nonstructural Antigen to MHC Class II–associated Invariant Chain Enhances T-cell Responses Induced by Vectored Vaccines in Nonhuman Primates

Despite viral vectors being potent inducers of antigen-specific T cells, strategies to further improve their immunogenicity are actively pursued. Of the numerous approaches investigated, fusion of the encoded antigen to major histocompatibility complex class II–associated invariant chain (Ii) has be...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Capone, Stefania, Naddeo, Mariarosaria, D'Alise, Anna Morena, Abbate, Adele, Grazioli, Fabiana, Del Gaudio, Annunziata, Del Sorbo, Mariarosaria, Esposito, Maria Luisa, Ammendola, Virginia, Perretta, Gemma, Taglioni, Alessandra, Colloca, Stefano, Nicosia, Alfredo, Cortese, Riccardo, Folgori, Antonella
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2014
Gaiak:
Original Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4015230/
https://ncbi.nlm.nih.gov/pubmed/24476798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2014.15
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