MHC class II invariant chain-adjuvanted viral vectored vaccines enhances T cell responses in humans

Strategies to enhance the induction of high magnitude T cell responses through vaccination are urgently needed. MHC class II associated invariant chain (Ii) plays a critical role in antigen presentation, forming MHC class II peptide complexes for the generation of CD4+ T cell responses. Pre-clinical...

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Detaylı Bibliyografya
Yayımlandı:Sci Transl Med
Asıl Yazarlar: Esposito, Ilaria, Cicconi, Paola, D’Alise, Anna Morena, Brown, Anthony, Esposito, Marialuisa, Swadling, Leo, Holst, Peter Johannes, Bassi, Maria Rosaria, Stornaiuolo, Mariano, Mori, Federica, Vassilev, Ventzislav, Li, Wenqin, Donnison, Timothy, Gentile, Chiara, Turner, Bethany, von Delft, Annette, Del Sorbo, Mariarosaria, Barra, Federica, Contino, Alessandra Maria, Abbate, Adele, Novellino, Ettore, Thomsen, Allan Randrup, Christensen, Jan Pravsgaard, Lahm, Armin, Grazioli, Fabiana, Ammendola, Virginia, Siani, Loredana, Colloca, Stefano, Klenerman, Paul, Nicosia, Alfredo, Dorrell, Lucy, Folgori, Antonella, Capone, Stefania, Barnes, Eleanor
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2020
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7610808/
https://ncbi.nlm.nih.gov/pubmed/32554708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aaz7715
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