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Recombinant Viral Vectored Vaccines Expressing Plasmodium chabaudi AS Apical Membrane Antigen 1: Mechanisms of Vaccine-Induced Blood-Stage Protection
Apical membrane antigen 1 (AMA1) is one of the leading candidate antigens for inclusion in a subunit vaccine against blood-stage malaria. However, the efficacy of antibody-inducing recombinant AMA1 protein vaccines in Phase IIa/b clinical trials to date remains disappointing. Here we describe the de...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3378655/ https://ncbi.nlm.nih.gov/pubmed/22504652 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1101106 |
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