A T Cell-Inducing Influenza Vaccine for the Elderly: Safety and Immunogenicity of MVA-NP+M1 in Adults Aged over 50 Years

BACKGROUND: Current influenza vaccines have reduced immunogenicity and are of uncertain efficacy in older adults. We assessed the safety and immunogenicity of MVA-NP+M1, a viral-vectored influenza vaccine designed to boost memory T cell responses, in a group of older adults. METHODS: Thirty voluntee...

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Auteurs principaux: Antrobus, Richard D., Lillie, Patrick J., Berthoud, Tamara K., Spencer, Alexandra J., McLaren, James E., Ladell, Kristin, Lambe, Teresa, Milicic, Anita, Price, David A., Hill, Adrian V. S., Gilbert, Sarah C.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2012
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3485192/
https://ncbi.nlm.nih.gov/pubmed/23118984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0048322
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