PD-1 pathway-mediated regulation of islet-specific CD4(+) T cell subsets in autoimmune diabetes

nork Martinov, Tijana, Spanier, Justin A., Pauken, Kristen E., Fife, Brian T.
Argitaratua izan da Immunoendocrinology (Houst) (2016)

Editorial: Fresh Ideas, Foundational Experiments: Immunology and Diabetes

nork Spanier, Justin A., Tse, Hubert M., Horwitz, Marc S., Fife, Brian T.
Argitaratua izan da Front Endocrinol (Lausanne) (2019)

Programmed death-1 culls peripheral accumulation of high affinity autoreactive CD4 T cells to protect against autoimmunity

nork Jiang, Tony T., Martinov, Tijana, Xin, Lijun, Kinder, Jeremy M., Spanier, Justin A., Fife, Brian T., Way, Sing Sing
Argitaratua izan da Cell Rep (2016)

Dual TCRα expression poses an autoimmune hazard by limiting T(reg) cell generation

nork Schuldt, Nathaniel J., Auger, Jennifer L., Spanier, Justin A., Martinov, Tijana, Breed, Elise R., Fife, Brian T., Hogquist, Kristin A., Binstadt, Bryce A.
Argitaratua izan da J Immunol (2017)

Interferon-gamma drives programmed death-ligand 1 expression on islet β cells to limit T cell function during autoimmune diabetes

nork Osum, Kevin C., Burrack, Adam L., Martinov, Tijana, Sahli, Nathanael L., Mitchell, Jason S., Tucker, Christopher G., Pauken, Kristen E., Papas, Klearchos, Appakalai, Balamurugan, Spanier, Justin A., Fife, Brian T.
Argitaratua izan da Sci Rep (2018)

Cutting Edge: Type 1 Diabetes Occurs despite Robust Anergy among Endogenous Insulin-Specific CD4 T Cells in NOD Mice

nork Pauken, Kristen E., Linehan, Jonathan L., Spanier, Justin A., Sahli, Nathanael L., Kalekar, Lokesh A., Binstadt, Bryce A., Moon, James J., Mueller, Daniel L., Jenkins, Marc K., Fife, Brian T.
Argitaratua 2013

Increased Effector Memory Insulin-Specific CD4(+) T Cells Correlate With Insulin Autoantibodies in Patients With Recent-Onset Type 1 Diabetes

nork Spanier, Justin A., Sahli, Nathanael L., Wilson, Joseph C., Martinov, Tijana, Dileepan, Thamotharampillai, Burrack, Adam L., Finger, Erik B., Blazar, Bruce R., Michels, Aaron W., Moran, Antoinette, Jenkins, Marc K., Fife, Brian T.
Argitaratua izan da Diabetes (2017)

T cell receptor cross-reactivity between similar foreign and self peptides influences naïve cell population size and autoimmunity

nork Nelson, Ryan W., Beisang, Daniel, Tubo, Noah J., Dileepan, Thamotharampillai, Wiesner, Darin L., Nielsen, Kirsten, Wüthrich, Marcel, Klein, Bruce S., Kotov, Dmitri I., Spanier, Justin A., Fife, Brian T., Moon, James J., Jenkins, Marc K.
Argitaratua izan da Immunity (2015)

Identification of autoreactive CD4(+) and CD8(+) T cell subsets resistant to PD-1 pathway blockade

nork Pauken, Kristen E, Nelson, Christine E, Martinov, Tijana, Spanier, Justin A, Heffernan, James R, Sahli, Nathanael L, Quarnstrom, Clare F, Osum, Kevin C, Schenkel, Jason M, Jenkins, Marc K, Blazar, Bruce R, Vezys, Vaiva, Fife, Brian T
Argitaratua izan da J Immunol (2015)

Programmed death-1 restrains the germinal center in type 1 diabetes

nork Martinov, Tijana, Swanson, Linnea A., Breed, Elise R., Tucker, Christopher G., Dwyer, Alexander J., Johnson, Jenna K., Mitchell, Jason S., Sahli, Nathanael L., Wilson, Joseph C., Singh, Lovejot M., Hogquist, Kristin A., Spanier, Justin A., Fife, Brian T.
Argitaratua izan da J Immunol (2019)

Development of canine PD-1/PD-L1 specific monoclonal antibodies and amplification of canine T cell function

nork Choi, Jin Wook, Withers, Sita S., Chang, Hong, Spanier, Justin A., De La Trinidad, Victoria L., Panesar, Harmanpreet, Fife, Brian T., Sciammas, Roger, Sparger, Ellen E., Moore, Peter F., Kent, Michael S., Rebhun, Robert B., McSorley, Stephen J.
Argitaratua izan da PLoS One (2020)

Efficient generation of monoclonal antibodies against peptide in the context of MHCII using magnetic enrichment

nork Spanier, Justin A., Frederick, Daniel R., Taylor, Justin J., Heffernan, James R., Kotov, Dmitri I., Martinov, Tijana, Osum, Kevin C., Ruggiero, Jenna L., Rust, Blake J., Landry, Samuel J., Jenkins, Marc K., McLachlan, James B., Fife, Brian T.
Argitaratua izan da Nat Commun (2016)

Thymic regulatory T cells arise via two distinct developmental programs

nork Owen, David L., Mahmud, Shawn A., Sjaastad, Louisa E., Williams, Jason B., Spanier, Justin A., Simeonov, Dimitre R., Ruscher, Roland, Huang, Weishan, Proekt, Irina, Miller, Corey N., Hekim, Can, Jeschke, Jonathan C., Aggarwal, Praful, Broeckel, Ulrich, LaRue, Rebecca S., Henzler, Christine M., Alegre, Maria-Luisa, Anderson, Mark S., August, Avery, Marson, Alexander, Zheng, Ye, Williams, Calvin B., Farrar, Michael A.
Argitaratua izan da Nat Immunol (2019)