Efficient generation of monoclonal antibodies against peptide in the context of MHCII using magnetic enrichment

Monoclonal antibodies specific for foreign antigens, auto-antigens, allogeneic antigens and tumour neo-antigens in the context of major histocompatibility complex II (MHCII) are highly desirable as novel immunotherapeutics. However, there is no standard protocol for the efficient generation of monoc...

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Publicado en:Nat Commun
Main Authors: Spanier, Justin A., Frederick, Daniel R., Taylor, Justin J., Heffernan, James R., Kotov, Dmitri I., Martinov, Tijana, Osum, Kevin C., Ruggiero, Jenna L., Rust, Blake J., Landry, Samuel J., Jenkins, Marc K., McLachlan, James B., Fife, Brian T.
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2016
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4909947/
https://ncbi.nlm.nih.gov/pubmed/27292946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms11804
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