Efficient generation of monoclonal antibodies against peptide in the context of MHCII using magnetic enrichment

Monoclonal antibodies specific for foreign antigens, auto-antigens, allogeneic antigens and tumour neo-antigens in the context of major histocompatibility complex II (MHCII) are highly desirable as novel immunotherapeutics. However, there is no standard protocol for the efficient generation of monoc...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nat Commun
Prif Awduron: Spanier, Justin A., Frederick, Daniel R., Taylor, Justin J., Heffernan, James R., Kotov, Dmitri I., Martinov, Tijana, Osum, Kevin C., Ruggiero, Jenna L., Rust, Blake J., Landry, Samuel J., Jenkins, Marc K., McLachlan, James B., Fife, Brian T.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2016
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4909947/
https://ncbi.nlm.nih.gov/pubmed/27292946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms11804
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