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Dual TCRα expression poses an autoimmune hazard by limiting T(reg) cell generation
Despite accounting for 10–30% of the T cell population in mice and humans, the role of dual TCR-expressing T cells in immunity remains poorly understood. It has been hypothesized that dual TCR T cells pose an “autoimmune hazard” by allowing self-reactive TCRs to escape thymic selection. We revisited...
Tallennettuna:
| Julkaisussa: | J Immunol |
|---|---|
| Päätekijät: | , , , , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2017
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5501482/ https://ncbi.nlm.nih.gov/pubmed/28539428 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1700406 |
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