Cutting Edge: Type 1 Diabetes Occurs despite Robust Anergy among Endogenous Insulin-Specific CD4 T Cells in NOD Mice

Insulin-specific CD4(+) T cells are required for type 1 diabetes. How these cells are regulated and how tolerance breaks down are poorly understood because of a lack of reagents. Therefore, we used an enrichment method and tetramer reagents to track insulin-specific CD4(+) T cells in diabetes-suscep...

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Detaylı Bibliyografya
Asıl Yazarlar: Pauken, Kristen E., Linehan, Jonathan L., Spanier, Justin A., Sahli, Nathanael L., Kalekar, Lokesh A., Binstadt, Bryce A., Moon, James J., Mueller, Daniel L., Jenkins, Marc K., Fife, Brian T.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2013
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3987747/
https://ncbi.nlm.nih.gov/pubmed/24123682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1301927
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