From eels to the importance of cancer biobanks

Por Span, Paul N
Publicado no Future Sci OA (2015)

International biobanks: do or do not?

Por Span, Paul N, Manders, Peggy
Publicado no Future Sci OA (2015)

Engineered microparticles delivering oxygen to enhance radiotherapy efficacy

Por Span, Paul N., Bussink, Johan, Kaanders, Johannes H. A. M.
Publicado no Proc Natl Acad Sci U S A (2016)

Can FDG PET predict radiation treatment outcome in head and neck cancer? Results of a prospective study

Por Schinagl, Dominic A. X., Span, Paul N., Oyen, Wim J., Kaanders, Johannes H. A. M.
Publicado em 2011

Regulation of TRIB3 mRNA and Protein in Breast Cancer

Por Wennemers, Marloes, Bussink, Johan, van den Beucken, Twan, Sweep, Fred C. G. J., Span, Paul N.
Publicado em 2012

Hypoxia stimulates migration of breast cancer cells via the PERK/ATF4/LAMP3-arm of the unfolded protein response

Por Nagelkerke, Anika, Bussink, Johan, Mujcic, Hilda, Wouters, Bradly G, Lehmann, Steffi, Sweep, Fred CGJ, Span, Paul N
Publicado em 2013

Predictive value of hypoxia, proliferation and tyrosine kinase receptors for EGFR-inhibition and radiotherapy sensitivity in head and neck cancer models

Por Stegeman, Hanneke, Kaanders, Johannes H., van der Kogel, Albert J., Iida, Mari, Wheeler, Deric L., Span, Paul N., Bussink, Johan
Publicado em 2013

Tumor Microenvironmental Changes Induced by the Sulfamate Carbonic Anhydrase IX Inhibitor S4 in a Laryngeal Tumor Model

Por Meijer, Tineke W. H., Bussink, Johan, Zatovicova, Miriam, Span, Paul N., Lok, Jasper, Supuran, Claudiu T., Kaanders, Johannes H. A. M.
Publicado em 2014

Treatment outcome and toxicity of intensity-modulated (chemo) radiotherapy in stage III non-small cell lung cancer patients

Por Govaert, Stephanie LA, Troost, Esther GC, Schuurbiers, Olga CJ, de Geus-Oei, Lioe-Fee, Termeer, Ariën, Span, Paul N, Bussink, Johan
Publicado em 2012

Interaction between hypoxia, AKT and HIF-1 signaling in HNSCC and NSCLC: implications for future treatment strategies

Por Stegeman, Hanneke, Span, Paul N, Peeters, Wenny JM, Verheijen, Marieke MG, Grénman, Reidar, Meijer, Tineke WH, Kaanders, Johannes HAM, Bussink, Johan
Publicado no Future Sci OA (2016)

Downregulation of Serine Protease HTRA1 Is Associated with Poor Survival in Breast Cancer

Por Lehner, Anna, Magdolen, Viktor, Schuster, Tibor, Kotzsch, Matthias, Kiechle, Marion, Meindl, Alfons, Sweep, Fred C. G. J., Span, Paul N., Gross, Eva
Publicado em 2013

Cathepsins B, L and cystatin C in cyst fluid of ovarian tumors

Por Kolwijck, Eva, Massuger, Leon F. A. G., Thomas, Chris M. G., Span, Paul N., Krasovec, Marta, Kos, Janko, Sweep, Fred C. G. J.
Publicado em 2009

Effect of hypoxia on the expression of αB-crystallin in head and neck squamous cell carcinoma

Por van de Schootbrugge, Chantal, Schults, Elisabeth MJ, Bussink, Johan, Span, Paul N, Grénman, Reidar, Pruijn, Ger JM, Kaanders, Johannes HAM, Boelens, Wilbert C
Publicado em 2014

ChIP-Seq of ERα and RNA polymerase II defines genes differentially responding to ligands

Por Welboren, Willem-Jan, van Driel, Marc A, Janssen-Megens, Eva M, van Heeringen, Simon J, Sweep, Fred CGJ, Span, Paul N, Stunnenberg, Hendrik G
Publicado em 2009

αB-crystallin stimulates VEGF secretion and tumor cell migration and correlates with enhanced distant metastasis in head and neck squamous cell carcinoma

Por van de Schootbrugge, Chantal, Bussink, Johan, Span, Paul N, Sweep, Fred CGJ, Grénman, Reidar, Stegeman, Hanneke, Pruijn, Ger JM, Kaanders, Johannes HAM, Boelens, Wilbert C
Publicado em 2013

Clinical significance of the nuclear receptor co-regulator DC-SCRIPT in breast cancer: an independent retrospective validation study

Por Sieuwerts, Anieta M, Ansems, Marleen, Look, Maxime P, Span, Paul N, de Weerd, Vanja, van Galen, Anne, Foekens, John A, Adema, Gosse J, Martens, John WM
Publicado em 2010

HIF-1α-independent hypoxia-induced rapid PTK6 stabilization is associated with increased motility and invasion

Por Pires, Isabel M, Blokland, Nina JG, Broos, Agnieke WT, Poujade, Flore-Anne, Senra, Joana M, Eccles, Suzanne A, Span, Paul N, Harvey, Amanda J, Hammond, Ester M
Publicado em 2014

Activation of AKT by hypoxia: a potential target for hypoxic tumors of the head and neck

Por Stegeman, Hanneke, Kaanders, Johannes H, Wheeler, Deric L, van der Kogel, Albert J, Verheijen, Marieke M, Waaijer, Stijn J, Iida, Mari, Grénman, Reidar, Span, Paul N, Bussink, Johan
Publicado em 2012

Combining radiotherapy with MEK1/2, STAT5 or STAT6 inhibition reduces survival of head and neck cancer lines

Por Stegeman, Hanneke, Kaanders, Johannes HAM, Verheijen, Marieke MG, Peeters, Wenny JM, Wheeler, Deric L, Iida, Mari, Grénman, Reidar, van der Kogel, Albert J, Span, Paul N, Bussink, Johan
Publicado em 2013

Hypoxia-induced p53 modulates both apoptosis and radiosensitivity via AKT

Por Leszczynska, Katarzyna B., Foskolou, Iosifina P., Abraham, Aswin G., Anbalagan, Selvakumar, Tellier, Céline, Haider, Syed, Span, Paul N., O’Neill, Eric E., Buffa, Francesca M., Hammond, Ester M.
Publicado no J Clin Invest (2015)