Molecular mechanisms of resistance to the EGFR monoclonal antibody cetuximab

Por Brand, Toni M, Iida, Mari, Wheeler, Deric L
Publicado em 2011

The Role of Src in Solid Tumors

Por Wheeler, Deric L., Iida, Mari, Dunn, Emily F.
Publicado em 2009

Dasatinib blocks cetuximab- and radiation-induced nuclear translocation of the epidermal growth factor receptor in head and neck squamous cell carcinoma

Por Li, Chunrong, Iida, Mari, Dunn, Emily F., Wheeler, Deric L.
Publicado em 2010

The Nuclear Epidermal Growth Factor Receptor Signaling Network and its Role in Cancer

Por Brand, Toni M., Iida, Mari, Li, Chunrong, Wheeler, Deric L.
Publicado em 2011

Nuclear EGFR Contributes to Acquired Resistance to Cetuximab

Por Li, Chunrong, Iida, Mari, Dunn, Emily F., Ghia, Amol J., Wheeler, Deric L.
Publicado em 2009

Yes and Lyn play a role in nuclear translocation of the Epidermal Growth Factor Receptor

Por Iida, Mari, Brand, Toni M., Campbell, David A, Li, Chunrong, Wheeler, Deric L.
Publicado em 2012

Mapping C-Terminal Transactivation Domains of the Nuclear HER Family Receptor Tyrosine Kinase HER3

Por Brand, Toni M., Iida, Mari, Luthar, Neha, Wleklinski, Matthew J., Starr, Megan M., Wheeler, Deric L.
Publicado em 2013

Nuclear EGFR as a Molecular Target in Cancer

Por Brand, Toni M., Iida, Mari, Luthar, Neha, Starr, Megan M., Huppert, Evan J., Wheeler, Deric L.
Publicado em 2013

Activation of Multiple ERBB Family Receptors Mediates Glioblastoma Cancer Stem-like Cell Resistance to EGFR-Targeted Inhibition

Por Clark, Paul A, Iida, Mari, Treisman, Daniel M, Kalluri, Haviryaji, Ezhilan, Sathyapriya, Zorniak, Michael, Wheeler, Deric L, Kuo, John S
Publicado em 2012

Targeting AKT with the allosteric AKT inhibitor MK-2206 in non-small cell lung cancer cells with acquired resistance to cetuximab

Por Iida, Mari, Brand, Toni M., Campbell, David A., Starr, Megan M., Luthar, Neha, Traynor, Anne M., Wheeler, Deric L.
Publicado em 2013

Human Epidermal Growth Factor Receptor 3 (HER3) Blockade with U3-1287/AMG888 Enhances the Efficacy of Radiation Therapy in Lung and Head and Neck Carcinoma

Por Li, Chunrong, Brand, Toni M., Iida, Mari, Huang, Shyhmin, Armstrong, Eric A., van der Kogel, Albert, Wheeler, Deric L.
Publicado em 2013

Predictive value of hypoxia, proliferation and tyrosine kinase receptors for EGFR-inhibition and radiotherapy sensitivity in head and neck cancer models

Por Stegeman, Hanneke, Kaanders, Johannes H., van der Kogel, Albert J., Iida, Mari, Wheeler, Deric L., Span, Paul N., Bussink, Johan
Publicado em 2013

Erlotinib is a viable treatment for tumors with acquired resistance to cetuximab

Por Brand, Toni M, Dunn, Emily F, Iida, Mari, Myers, Rebecca A, Kostopoulos, Kellie T, Li, Chunrong, Peet, Chimera R, Wheeler, Deric L
Publicado em 2011

Epidermal growth factor receptor cooperates with Src family kinases in acquired resistance to cetuximab

Por Wheeler, Deric L., Iida, Mari, Kruser, Tim J., Nechrebecki, Meghan M., Dunn, Emily F., Armstrong, Eric A., Huang, Shyhmin, Harari, Paul M.
Publicado em 2009

Dasatinib sensitizes KRAS mutant colorectal tumors to cetuximab

Por Dunn, Emily F., Iida, Mari, Myers, Rebecca A., Hintz, Kylee A., Campbell, David A., Armstrong, Eric A., Li, Chunrong, Wheeler, Deric L.
Publicado em 2010

Dual targeting of PI3K and MEK enhances the radiation response of K-RAS mutated non-small cell lung cancer

Por Toulany, Mahmoud, Iida, Mari, Keinath, Simone, Iyi, Firdevs F., Mueck, Katharina, Fehrenbacher, Birgit, Mansour, Wael Y., Schaller, Martin, Wheeler, Deric L., Rodemann, H. Peter
Publicado no Oncotarget (2016)

Nuclear Epidermal Growth Factor Receptor is a Functional Molecular Target in Triple-Negative Breast Cancer

Por Brand, Toni M., Iida, Mari, Luthar, Neha, Kostopoulos, Kellie T., Corrigan, Kelsey L., Wleklinski, Matthew J., Yang, David, Wisinski, Kari B., Salgia, Ravi, Wheeler, Deric L.
Publicado em 2014

Sym004, a Novel EGFR Antibody Mixture, Can Overcome Acquired Resistance to Cetuximab

Por Iida, Mari, Brand, Toni M, Starr, Megan M, Li, Chunrong, Huppert, Evan J, Luthar, Neha, Pedersen, Mikkel W, Horak, Ivan D, Kragh, Michael, Wheeler, Deric L
Publicado em 2013

Overcoming acquired resistance to cetuximab by dual targeting HER family receptors with antibody-based therapy

Por Iida, Mari, Brand, Toni M, Starr, Megan M, Huppert, Evan J, Luthar, Neha, Bahrar, Harsh, Coan, John P, Pearson, Hannah E, Salgia, Ravi, Wheeler, Deric L
Publicado no Mol Cancer (2014)

AXL mediates resistance to cetuximab therapy

Por Brand, Toni M., Iida, Mari, Stein, Andrew P., Corrigan, Kelsey L., Braverman, Cara, Luthar, Neha, Toulany, Mahmoud, Gill, Parkash S., Salgia, Ravi, Kimple, Randall J., Wheeler, Deric L.
Publicado em 2014