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Human Epidermal Growth Factor Receptor 3 (HER3) Blockade with U3-1287/AMG888 Enhances the Efficacy of Radiation Therapy in Lung and Head and Neck Carcinoma

HER3 is a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. In the present study, we investigated the capacity of the HER3 blocking antibody, U3-1287/AMG888, to modulate the in vitro and in vivo radiation response of human squamous cell carcinomas of the lung...

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Detalhes bibliográficos
Main Authors: Li, Chunrong, Brand, Toni M., Iida, Mari, Huang, Shyhmin, Armstrong, Eric A., van der Kogel, Albert, Wheeler, Deric L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3901945/
https://ncbi.nlm.nih.gov/pubmed/23998444
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