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Targeting AKT with the allosteric AKT inhibitor MK-2206 in non-small cell lung cancer cells with acquired resistance to cetuximab

The epidermal growth factor receptor (EGFR) is a central regulator of tumor progression in human cancers. Cetuximab is an anti-EGFR monoclonal antibody that has been approved for use in oncology. Despite clinical success the majority of patients do not respond to cetuximab and those who initially re...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Iida, Mari, Brand, Toni M., Campbell, David A., Starr, Megan M., Luthar, Neha, Traynor, Anne M., Wheeler, Deric L.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Landes Bioscience 2013
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3813564/
https://ncbi.nlm.nih.gov/pubmed/23760490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.24342
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