Combining radiotherapy with MEK1/2, STAT5 or STAT6 inhibition reduces survival of head and neck cancer lines

BACKGROUND: Kinases downstream of growth factor receptors have been implicated in radioresistance and are, therefore, attractive targets to improve radiotherapy outcome in head and neck squamous cell carcinoma (HNSCC) patients. METHODS: An antibody-based array was used to quantify the expression lev...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Stegeman, Hanneke, Kaanders, Johannes HAM, Verheijen, Marieke MG, Peeters, Wenny JM, Wheeler, Deric L, Iida, Mari, Grénman, Reidar, van der Kogel, Albert J, Span, Paul N, Bussink, Johan
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2013
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3842630/
https://ncbi.nlm.nih.gov/pubmed/24192080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-12-133
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