Dasatinib Inhibits DNA Repair after Radiotherapy Specifically in pSFK-Expressing Tumor Areas in Head and Neck Xenograft Tumors

Src family kinases (SFKs) have been implicated in resistance to both radiation and epidermal growth factor receptor (EGFR) inhibition. Therefore, we investigated whether inhibition of SFK through dasatinib (DSB) can enhance the effect of radiotherapy in two in vivo human head and neck squamous cell...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Stegeman, Hanneke, Span, Paul N, Rijken, Paul F J W, Cockx, Simone C, Wheeler, Deric L, Iida, Mari, van der Kogel, Albert J, Kaanders, Johannes H A M, Bussink, Johan
Format: Artigo
Sprog:Inglês
Udgivet: Neoplasia Press Inc. 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3730016/
https://ncbi.nlm.nih.gov/pubmed/23908684
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker