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Activation of AKT by hypoxia: a potential target for hypoxic tumors of the head and neck
BACKGROUND: Only a minority of cancer patients benefits from the combination of EGFR-inhibition and radiotherapy in head and neck squamous cell carcinoma (HNSCC). A potential resistance mechanism is activation of EGFR and/or downstream pathways by stimuli in the microenvironment. The aim of this stu...
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Главные авторы: | , , , , , , , , , |
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Формат: | Artigo |
Язык: | Inglês |
Опубликовано: |
BioMed Central
2012
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Предметы: | |
Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3517352/ https://ncbi.nlm.nih.gov/pubmed/23046567 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-12-463 |
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