Interaction between hypoxia, AKT and HIF-1 signaling in HNSCC and NSCLC: implications for future treatment strategies

BACKGROUND: Hypoxia is a negative prognostic factor and this study investigated the relationship between hypoxia, hypoxia inducible factor 1 (HIF-1) and AKT signaling in head and neck squamous cell carcinoma (HNSCC) and non-small-cell lung cancer (NSCLC). RESULTS/METHODOLOGY: pAKT was induced by hyp...

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Detalhes bibliográficos
Publicado no:Future Sci OA
Main Authors: Stegeman, Hanneke, Span, Paul N, Peeters, Wenny JM, Verheijen, Marieke MG, Grénman, Reidar, Meijer, Tineke WH, Kaanders, Johannes HAM, Bussink, Johan
Formato: Artigo
Idioma:Inglês
Publicado em: Future Science Ltd 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5137923/
https://ncbi.nlm.nih.gov/pubmed/28031935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4155/fso.15.84
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