Endothelial cell CD36 deficiency prevents normal angiogenesis and vascular repair

Por Bou Khzam, Lara, Son, Ni-Huiping, Mullick, Adam E, Abumrad, Nada A, Goldberg, Ira J
Publicado no Am J Transl Res (2020)

Glycemic Reduction Alters White Blood Cell Counts and Inflammatory Gene Expression in Diabetes

Por Fang, Xiang, Dorcely, Brenda, Ding, Xi-ping, Yin, Shi, Son, Ni-Huiping, Hu, Shi-Lian, Goldberg, Ira J.
Publicado no J Diabetes Complications (2018)

Sequestration of fatty acids in triglycerides prevents endoplasmic reticulum stress in an in vitro model of cardiomyocyte lipotoxicity

Por Bosma, Madeleen, Dapito, Dianne H., Drosatos-Tampakaki, Zoi, Huiping-Son, Ni, Huang, Li-Shin, Kersten, Sander, Drosatos, Konstantinos, Goldberg, Ira J.
Publicado no Biochim Biophys Acta (2014)

PPARγ-induced cardiolipotoxicity in mice is ameliorated by PPARα deficiency despite increases in fatty acid oxidation

Por Son, Ni-Huiping, Yu, Shuiqing, Tuinei, Joseph, Arai, Kotaro, Hamai, Hiroko, Homma, Shunichi, Shulman, Gerald I., Abel, E. Dale, Goldberg, Ira J.
Publicado em 2010

PPARγ Activation Prevents Sepsis-Related Cardiac Dysfunction and Mortality in Mice: Drosatos et al: PPARγ Treats Septic Cardiac Dysfunction

Por Drosatos, Konstantinos, Khan, Raffay S., Trent, Chad M., Jiang, Hongfeng, Son, Ni-Huiping, Blaner, William S., Homma, Shunichi, Schulze, P. Christian, Goldberg, Ira J.
Publicado em 2013

PPARγ-induced cardiolipotoxicity in mice is ameliorated by PPARα deficiency despite increases in fatty acid oxidation

Por Son, Ni-Huiping, Yu, Shuiqing, Tuinei, Joseph, Arai, Kotaro, Hamai, Hiroko, Homma, Shunichi, Shulman, Gerald I., Abel, E. Dale, Goldberg, Ira J.
Publicado no J Clin Invest (2010)

Cardiomyocyte expression of PPARγ leads to cardiac dysfunction in mice

Por Son, Ni-Huiping, Park, Tae-Sik, Yamashita, Haruyo, Yokoyama, Masayoshi, Huggins, Lesley A., Okajima, Kazue, Homma, Shunichi, Szabolcs, Matthias J., Huang, Li-Shin, Goldberg, Ira J.
Publicado em 2007

Cardiomyocyte Aldose Reductase Causes Heart Failure and Impairs Recovery from Ischemia

Por Son, Ni-Huiping, Ananthakrishnan, Radha, Yu, Shuiqing, Khan, Raffay S., Jiang, Hongfeng, Ji, Ruiping, Akashi, Hirokazu, Li, Qing, O'Shea, Karen, Homma, Shunichi, Goldberg, Ira J., Ramasamy, Ravichandran
Publicado em 2012

Rescue of heart lipoprotein lipase-knockout mice confirms a role for triglyceride in optimal heart metabolism and function

Por Khan, Raffay S., Lin, Yan, Hu, Yunying, Son, Ni-Huiping, Bharadwaj, Kalyani G., Palacios, Carla, Chokshi, Aalap, Ji, Ruiping, Yu, Shuiqing, Homma, Sunichi, Schulze, P. Christian, Tian, Rong, Goldberg, Ira J.
Publicado em 2013

Regulation of Insulin Receptor Pathway and Glucose Metabolism by CD36 Signaling

Por Samovski, Dmitri, Dhule, Pallavi, Pietka, Terri, Jacome-Sosa, Miriam, Penrose, Eric, Son, Ni-Huiping, Flynn, Charles Robb, Shoghi, Kooresh I., Hyrc, Krzysztof L., Goldberg, Ira J., Gamazon, Eric R., Abumrad, Nada A.
Publicado no Diabetes (2018)

Human Aldose Reductase Expression Accelerates Atherosclerosis in Diabetic apoE−/− Mice

Por Vedantham, Srinivasan, Noh, HyeLim, Ananthakrishnan, Radha, Son, Ni, Hallam, Kellie, Hu, Yunying, Yu, Shuiquing, Shen, Xiaoping, Rosario, Rosa, Lu, Yan, Ravindranath, Thyyar, Drosatos, Konstantinos, Huggins, Lesley Ann, Schmidt, Ann Marie, Goldberg, Ira J., Ramasamy, Ravichandran
Publicado em 2011

Mice with cardiac overexpression of PPARγ have impaired repolarization and spontaneous fatal ventricular arrhythmias (Morrow, PPARγ overexpression induces fatal arrhythmias)

Por Morrow, John P., Katchman, Alexander, Son, Ni-Huiping, Trent, Chad M., Khan, Raffay, Shiomi, Takayuki, Huang, Haiyan, Amin, Vaibhav, Lader, Joshua M., Vasquez, Carolina, Morley, Gregory E., D'Armiento, Jeanine, Homma, Shunichi, Goldberg, Ira J., Marx, Steven O.
Publicado em 2011

CD36 Deficiency Impairs the Small Intestinal Barrier and Induces Subclinical Inflammation in Mice

Por Cifarelli, Vincenza, Ivanov, Stoyan, Xie, Yan, Son, Ni-Huiping, Saunders, Brian T., Pietka, Terri A., Shew, Trevor M., Yoshino, Jun, Sundaresan, Sinju, Davidson, Nicholas O., Goldberg, Ira J., Gelman, Andrew E., Zinselmeyer, Bernd H., Randolph, Gwendalyn J., Abumrad, Nada A.
Publicado no Cell Mol Gastroenterol Hepatol (2016)

Kidney triglyceride accumulation in the fasted mouse is dependent upon serum free fatty acids

Por Scerbo, Diego, Son, Ni-Huiping, Sirwi, Alaa, Zeng, Lixia, Sas, Kelli M., Cifarelli, Vincenza, Schoiswohl, Gabriele, Huggins, Lesley-Ann, Gumaste, Namrata, Hu, Yunying, Pennathur, Subramaniam, Abumrad, Nada A., Kershaw, Erin E., Hussain, M. Mahmood, Susztak, Katalin, Goldberg, Ira J.
Publicado no J Lipid Res (2017)

Adipose-specific Lipoprotein Lipase Deficiency More Profoundly Affects Brown than White Fat Biology

Por Garcia-Arcos, Itsaso, Hiyama, Yaeko, Drosatos, Konstantinos, Bharadwaj, Kalyani G., Hu, Yunying, Son, Ni Huiping, O'Byrne, Sheila M., Chang, Chuchun L., Deckelbaum, Richard J., Takahashi, Manabu, Westerterp, Marit, Obunike, Joseph C., Jiang, Hongfeng, Yagyu, Hiroaki, Blaner, William S., Goldberg, Ira J.
Publicado em 2013

Cardiomyocyte-specific Loss of Diacylglycerol Acyltransferase 1 (DGAT1) Reproduces the Abnormalities in Lipids Found in Severe Heart Failure

Por Liu, Li, Trent, Chad M., Fang, Xiang, Son, Ni-Huiping, Jiang, HongFeng, Blaner, William S., Hu, Yunying, Yin, Yu-Xin, Farese, Robert V., Homma, Shunichi, Turnbull, Andrew V., Eriksson, Jan W., Hu, Shi-Lian, Ginsberg, Henry N., Huang, Li-Shin, Goldberg, Ira J.
Publicado em 2014

ApoC-III inhibits clearance of triglyceride-rich lipoproteins through LDL family receptors

Por Gordts, Philip L.S.M., Nock, Ryan, Son, Ni-Huiping, Ramms, Bastian, Lew, Irene, Gonzales, Jon C., Thacker, Bryan E., Basu, Debapriya, Lee, Richard G., Mullick, Adam E., Graham, Mark J., Goldberg, Ira J., Crooke, Rosanne M., Witztum, Joseph L., Esko, Jeffrey D.
Publicado no J Clin Invest (2016)

Endothelial cell CD36 optimizes tissue fatty acid uptake

Por Son, Ni-Huiping, Basu, Debapriya, Samovski, Dmitri, Pietka, Terri A., Peche, Vivek S., Willecke, Florian, Fang, Xiang, Yu, Shui-Qing, Scerbo, Diego, Chang, Hye Rim, Sun, Fei, Bagdasarov, Svetlana, Drosatos, Konstantinos, Yeh, Steve T., Mullick, Adam E., Shoghi, Kooresh I., Gumaste, Namrata, Kim, KyeongJin, Huggins, Lesley-Ann, Lhakhang, Tenzin, Abumrad, Nada A., Goldberg, Ira J.
Publicado no J Clin Invest (2018)