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PPARγ Activation Prevents Sepsis-Related Cardiac Dysfunction and Mortality in Mice: Drosatos et al: PPARγ Treats Septic Cardiac Dysfunction
BACKGROUND: Cardiac dysfunction with sepsis is associated with both inflammation and reduced fatty acid oxidation (FAO). We hypothesized that energy deprivation accounts for sepsis-related cardiac dysfunction. METHODS AND RESULTS: E. coli lipopolysaccharide (LPS) administered to C57BL/6 mice (WT) in...
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Main Authors: | , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2013
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3690188/ https://ncbi.nlm.nih.gov/pubmed/23572494 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCHEARTFAILURE.112.000177 |
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