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Diacylglycerol acyl transferase 1 overexpression detoxifies cardiac lipids in PPARγ transgenic mice
Accumulation of excess lipids is associated with heart failure. The effects of transgenic expression of diacylglycerol acyl transferase 1 (DGAT1) in cardiomyocytes is controversial. We explored whether mice expressing DGAT1 via the myosin heavy chain (MHC) promoter develop heart dysfunction with agi...
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Huvudupphovsmän: | , , , , , , , |
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Materialtyp: | Artigo |
Språk: | Inglês |
Publicerad: |
The American Society for Biochemistry and Molecular
Biology
2012
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Ämnen: | |
Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3540859/ https://ncbi.nlm.nih.gov/pubmed/22628613 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M024208 |
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