Diacylglycerol acyl transferase 1 overexpression detoxifies cardiac lipids in PPARγ transgenic mice

Accumulation of excess lipids is associated with heart failure. The effects of transgenic expression of diacylglycerol acyl transferase 1 (DGAT1) in cardiomyocytes is controversial. We explored whether mice expressing DGAT1 via the myosin heavy chain (MHC) promoter develop heart dysfunction with agi...

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Detalhes bibliográficos
Main Authors: Liu, Li, Yu, Shuiqing, Khan, Raffay S., Homma, Shunichi, Schulze, P. Christian, Blaner, William S., Yin, Yuxin, Goldberg, Ira J.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2012
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Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3540859/
https://ncbi.nlm.nih.gov/pubmed/22628613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M024208
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